Is yk11 a steroid. So it does work on the androgen receptors to build muscle.

very happy with the results over 3 months at 20mg per day along with 250mg test E, mk677, cardarine, otc vitamins with a good diet and felt the best I ever felt in a long time at 52 yrs old Jul 20, 2015 · Jul 10, 2020. YK11 is a SARM and myostatin inhibitor in one Japanese researchers are doing tests with a new SARM , which according to the first publications has a Jan 28, 2024 · Damn I was reading 10mg of oral yk11 a day for a first timer was fine. Hi, Alex Rogers here, supplement manufacturing expert. However, SARMs are unregulated and unapproved in the U. Reactions: Jbswole40. YK11 Stack info. Feb 21, 2023 · The 7 Best SARMs to Take. It has been proven that the compound promotes muscle growth, muscle retention, and the growth of new muscle cells. Oh definitely, as I don't want to risk any major muscle tears right now as had a few minor ones over past few years mostly because I got a bit greedy lol. I’m around 13% body fat. Currently there is no universal nomenclature for SARMs, however there is a world accepted nomenclature for steroids which YK-11 YK-11. Jun 20, 2020 · I suspect that there is also a marketing reason behind it being labeled as a SARM because structurally it’s clearly closer to a steroid than a SARM, is to avoid unwanted attention. The Science. YK-11 for sale - Discover top-notch quality / lab tested SARMs in US / Canada Steroids store. All that being said, YK-11 is uniquely classified as both a SARM and steroid, due to its molecular and chemical structure. Like any of the SARMs, a stack is a great way of amplifying and complementing the actions of YK11. They claim that they managed to gain size every week while using it, but strength will also increase rapidly. 19 votes, 13 comments. Dec 4, 2015 · The current information on the internet about YK-11, is some what incorrect and by no means complete. Jul 8, 2024 · Selective androgen receptor modulators (SARMs) are a group of products that are sometimes marketed as workout supplements. . R. As a result, inhibiting it in your body helps to increase your ability to bulk up quickly and efficiently Jul 31, 2017 · The conflict stems from the fact that there is no universally accepted nomenclature for SARMs but there is a widely accepted steroid nomenclature. Mar 20, 2024 · The truth is, YK11 is a synthetic steroid that has been created by directly altering the chemical structure of DHT (a hormone that occurs naturally in the body) – a stronger form of testosterone. Exerting its androgenic effects and inhibiting myostatin while combined with a potent steroid stack. On the other hand, it’s also considered a selective androgen receptor modulator (SARM). Ms stimulate muscle growth mainly by attaching to and activating the androgen receptor. As YK11 is an experimental drug candidate and a non-approved substance for humans, scientific data on its metabolism is scarce. Board Rep. Apr 18, 2023 · YK-11 is the only SARM that has a steroidal structure and the only SARM that also acts as a myostatin inhibitor. S4. my main concern with stacking it is if it will interfere with each other like Rob each other of receptors or anything like that. YK11 To validate YK11's anabolic potential, we performed a molecular docking analysis with the androgen receptor (AR), which showed high affinity with YK11, highlighting hydrogen interactions in Arg752. They don't work as well, and hence they don't have as many side effects. Jan 18, 2017 · A methyl group is an alkyl with the formula CH 3. I've seen a lot of people say that "YK-11 is a SARM, not a steroid". If you're going to run a test base then you might as well use Tbol or var instead. If you want a DHT derivative Anavar or Winny are good. Of course, SARMs are on average much weaker than steroids are but this compound is actually very strong and is comparable to steroids in power. As most of you know, steroids/S. Depending on where you're reading, I've read YK-11 is a sarm, a DHT-derived steroid, and it that it only behaves similarly to DHT. There are two kinds of… This guy is nuts. YK11 and SARMs work differently in the body and may have different side effects. YK11 is methylated, 5A reduced and a 19-nor derivative that hasn't been studied much at all. The general wisdom is that stacking SARMs is a waste, and for good reason, it’s the same reason you wouldent take multiple orals on an AAS cycle, however , since YK-11 more closely mirrors an oral steroid (or is one depending on who you ask) would it provide synergy with LGD. YK11 has garnered attention in the bodybuilding community for its potential as a safe and effective alternative to traditional anabolic steroids. com. May 25, 2020 · I've read a few comments saying S23 is very strong - my impression is that the pecking order of Sarms strength from weakest to strongest goes as follows: Ostarine. Triceps was more defined. Oct 5, 2017 · Interesting question. YK-11. Oct 27, 2019 · Hi everyone quick question about myostatin and yk11 why is yk11 not a must for all cycles if 05:12 AM in ANABOLIC STEROIDS - QUESTIONS & ANSWERS. Nov 4, 2022 · Russo wanted to answer a quick question about his use of YK-11 and why it pertains to his current cycle. By stimulating them, the substance is able to regulate prostate function, liver Dec 12, 2023 · The use of yk11 could stimulate muscle growth, similar to anabolic steroids, but without many of their side effects. My legs and chest also experienced growth. YK 11 is a type of SARM that focuses on androgen receptors. It’s easier to market SARMs than steroids because steroids are illegal. S23. However, this is a very powerful compound, arguably the most of any SARM, with such similarities to anabolic steroids that some have argued it should be treated as such. Including different injections, needles, and tablets at a huge discount. Aug 9, 2022 · YK11 is also known to increase muscle mass and strength, and to decrease body fat. 00 out of 5 based on 12 customer ratings. I've got some Ostarine, RAD-140, and LGD-4033 to cycle with my TRT, and I want one more compound to try out - so I'm debating S23 and YK-11. His experimentation is based around tweaking his myo Mar 10, 2024 · Ligandrol LGD-4033 is a selective androgenic receptor modulator (SARM) that was developed by Ligand Pharmaceuticals. Recently started S23 with test and preferred the the s23 over the other SARMs. We promise to offer you high-quality steroids. This cycle is reserved for the pros. 5mg morning 5mg evening . It targets those receptors that are specifically in muscle and bone tissues, avoiding alternative areas such as the prostate, and prejudices aspect effects that may turn up with elevated androgenic hormone. Anabolic steroids are known for their ability to promote muscle growth, but they often come with a range of unwanted side effects. 99. #118. Unlike traditional anabolic steroids, YK11 selectively binds to androgen receptors, focusing its anabolic effects on muscle cell growth without the negative side effects typically associated with steroids. It is primarily a mass building SARM that was originally developed to treat muscle-wasting conditions. Anecdotal experiences have shown an increase of up to 10lbs YK11 is a powerful and unique SARM that not only functions as a muscle builder but also as a myostatin inhibitor, encouraging muscle growth by decreasing its regulation. Legal SARMs are a good alternative to illegal and unsafe steroids. Either way, it has the potential to affect the prostate in some people, like DHT, which is further stated through dogdog's experience. Stacking with rad140 is a retarded idea, your test/est are going to be so crushed you will feel like shit. Dec 19, 2023 · However, it’s important to take these steroids with caution as anything can go wrong at any time. YK-11 stacked with LGD and Enclo. While it is not as suppressive as synthetic steroids, YK11 can cause mild testosterone suppression. Cycle Length and PCT. As a supplement manufacturing expert, I know about Nov 19, 2015 · YK11 acts as a gene-selective agonist of AR in MDA-MB 453 cells. Rated 5. YK11 becomes attached to the androgen receptors found in the body. All the common and most demanding products from the world of bodybuilding are available at our shop. I have cycled injectable YK-11 prior and I will say that it's definitely a game changer. YK11. YK11 is a partial agonist of the steroid receptor and mimics the effect of a full steroid hormone SARM. Furthermore, YK11 does not induce amino/carboxyl-terminal (N/C) interaction and prevents 5-α-dihydrotestosterone (DHT)-mediated N/C interaction. Nomenclature is a system of names or terms, or the rules for forming these terms in a particular field of arts or sciences. Because it is known Akt-signaling is a key regulator of androgen-mediated osteoblast differentiation, YK11 has osteogenic activity as well as androgen. If it delivers it could literally be a case of transforming your physique within a single cycle. Nov 15, 2023 · It seems good, at least on paper, as it's both a SARM (partial AR agonist) and myostain inhibitor. Legal And Safe YK 11 and RAD 140 Alternatives. BENEFITS: Testolone is a powerful bulking SARM that makes it easier and faster for you to gain muscle. It is known for its potency and is often compared to steroids in terms of effectiveness. It has been reported by athletes that they gained muscle and lost fat after using this particular drug for some period during both their bulking phase as well as cutting cycle(s). YK-11 is based on 5-α-dihydrotestosterone (DHT) which is a stronger form of testosterone that targets androgen receptors in the prostate, sex organs, hair, and Oct 11, 2023 · Bodybuilders use a YK11 dosage anywhere from 5mg to 20mg a day, but the sweetspot that most male users prefer is 10mg a day. It's also expensive as shit. Although YK-11 is associated with fewer side effects, it is not completely free of them, as discussed above. But in all honesty bro, RAD140 and YK11 kill it all in my opinion. YK11 stands out because, as a SARM, it selectively binds to androgen receptors, offering muscle-building benefits without the typical May 13, 2016 · 121. Dec 2, 2023 · Guys who have a history of steroid use don’t shy away from stating that YK-11 is as powerful or even more so than steroids like testosterone taken at performance doses. Keeping optimal levels of YK11 in your bloodstream is essential. YK-11 is not a SARM. Whether or not you should implement PCT after a YK11 cycle depends on various factors, including the dosage used and the cycle length. Oct 20, 2023 · SARMS serve as alternative to anabolic-androgenic steroids, with fewer limitations, also exhibiting high-bioavailability. May 15, 2021. However, like all anabolic steroids, YK 11 comes with a YK11 is a compound that is gaining a lot of traction within the bodybuilding world. 60 Capsules per pouch. In research, YK11 seems to have a selective function on the receptors of androgen which is where the similarities start and end as a SARM. I had changed my body composition in just six weeks with YK11. It’s considered to be one of the most powerful SARMs on the market and it’s actually comparable to certain steroids in its effectiveness. So it does work on the androgen receptors to build muscle. In this study, we show that treatment of YK11 and dihydrotestosterone (DHT) accelerated cell proliferation and mineralization in MC3T3-E1 mouse osteoblast cells. Jul 16, 2022. If you're going to run it you'd be best to run a test base. My stats are 5’5’’ 165 pounds. Since the YK11 does not have data on its action from animal or human studies, to answer the question we can rely on what the law considers a steroid or not (in the United States based on DASCA 2014 Feb 21, 2021 · YK11 is a known myostatin inhibitor. The reason that YK-11 is not a SARM is that it has a steroid nomenclature. May 15, 2022 · May 15, 2022. Jun 21, 2019 · YK11 is actually a myostatin inhibitor. 50ml bottles | almost 70% more volume compared to 30ml. For example, if you choose 10mg/day as your dose, you would take 5mg every 12 hours. Anyone that tries to extrapolate its properties based solely on its structure is probably trying to sell you something. The YK11 will work synergistically with RAD Here’s what we do know about YK11. ) It functions as a myostatin inhibitor. Jun 19, 2022 · And that is because they found it highly effective at building muscle tissue. My arms and back both looked fuller and my shoulders appeared wider. YK11 makes it's own class of anabolics and it functions similarly to a synthetic steroid. 2. Joined Jun Jun 7, 2023 · YK11 and Bodybuilding. Apr 3, 2024 · It is surreal just how much this SARM-steroid can improve your lifts; you have to try it out for yourself to really see it. Basically everything you want in a bulking cycle is covered by RAD-140. According to results obtained from clinical trials, humans can take up to 222 mg per day of Ligandrol for 14 consecutive days. This chemical is a by-product of various weightlifting and exercise processes. YK 11 side effects Oct 27, 2021 · YK-11 is a partial agonist of the androgen receptor. YK11 is a steroid. Always on TRT. Here is a published study on YK11 that is worth a read. YK11 - 5mg - Deus Medical ACTIVE HALF-LIFE: 12 hours CLASSIFICATION: Myostatin inhibitor DOSAGE: 10-15 mg/day ACNE: WATER RETENTION: HBR Being selective in its operation, YK-11 safely provides the long-awaited benefits of anabolic steroids when used responsibly. He jumps on post and points out things said in the original post and try’s saying they’re incorrect. However, it should be used with caution. 5). Mostly in muscle and bone tissue, but also more widely. Oct 8, 2023 · Testolone RAD-140 Structure. RAD 140 (Testolone) RAD 140 is the most widely recognized SARM for good reason, as it significantly increases muscle mass and fat-burning. #1. There is a lot of confusion about whether it is a steroid or whether it is a SARM. YK-11, a cutting-edge myostatin inhibitor, is renown for its dynamic role in bodybuilding, unlocking the potential for muscle gains and strength. Yes. In contrast, all other SARMs have a nonsteroidal structure. YK11 is a steroid made by directly altering the chemical structure of DHT. YK-11 has a very unique structure which shares more in common with steroids than it does with SARMs. Never taken it though just in case your thinking it's some little compound it doesn't seem like it to my knowledge Yk11 is a steroid and has all the side effects associated with steroids. YK11 works by inhibiting the creation of Myostatin in your body. Dec 8, 2023 · I don’t recommend pairing Clenbuterol with SARMs. Let’s address number one first. true Apr 5, 2024 · YK11 is a steroidal SARM (Selective Androgen Receptor Modulator). Now here is where things get tricky because there are multiple theories surrounding YK 11 SARM. For sheer size and cost effectiveness mandro is good, but for a leaner look and being in a better mood I’d day that yk11 and rad140 is better, but it’s going to cost a little more to run the amount you need for 8 weeks. The guys saying "oh best sarm hell yeah" are commenting on a steroid not a SARM. YK-11 is similar to DHT with a steroidal backbone and a partial agonist effect. For those that aren’t sure, DHT is a stronger form of testosterone that targets androgen receptors in the liver, sex organs, prostate and hair. Myostatin is a protein that prevents muscle growth. 35 g/kg), EXE (swimming protocol), and EXE+YK11. How YK11 Works It is high time to order online steroids UK from our online store steroidsanctuary. They can have serious side effects Nov 21, 2020 · YK-11 is a myostatin inhibitor so it doesn’t promote sex steroid hormone increases like an illegal steroid; however, some of its side effects are similar to that of a low-level prohormone. Do your due diligence to remember the half-life of YK11 is unclear but most take it twice per day. @Mac11wildcat has shared his protocol for its use, an example of excellent bro science (as opposed to bad bro science, this is very good): Mac11wildcat protocol (YK-11): YK-11 treatment mid-cycle (observed that MSTN peaks mid-cycle in his Oct 20, 2023 · SARMS serve as alternative to anabolic-androgenic steroids, with fewer limitations, also exhibiting high-bioavailability. Jan 3, 2024 · YK-11 is a new synthetic steroid (it is actually a steroidal SARM, making it easy to categorise it as both). Even the most veteran users found in forums aren’t exactly sure. RAD-140. Once the substance has attached itself to an androgen receptor, it sends signals to the muscles. YK11 and sarms in general are very new and haven't had much study on them so if anyone is concerned on YK's safety stick with a real sarm. The answer is – it is a SARM. The answer to both questions is: yes. 16 votes, 34 comments. YK-11 is a 17aa anabolic steroid. Since YK11 SARM is a synthetic steroid based on 5-a-dihydrotestosterone (DHT) – a natural hormone our bodies produce – it has the potential to deliver fast muscle growth. Click to expand Yea you can use yk11 with steroids. . Is YK-11 a Steroid or a SARM? Apr 5, 2024 · YK11 is a very interesting compound, with it being both a SARM and a steroid. If you want a working cutting stack, then go with this one: Week 1-12 – 30mg/day SR9009 (Stenabolic) Week 1-12 – 50mg/day S4 (Andarine) 25mg in the morning and 25mg 4-6 hours later. Thus, YK11 activates AR without causing N/C interaction, which may in turn be responsible for the partially agonistic nature of YK11 observed in the ARE-luciferase reporter system. Jun 24, 2024 · YK11 is a very tricky compound to understand. During the five-week protocol, we divided male Wistar rats into the following groups: Control, YK11 (0. YK-11 causes full HPTA shutdown. Important First YK11 is a very unique SARM, which also makes it a little bit confusing to understand. The effect of YK11 on gene expression relative to that of androgen agonist varies depending on the gene context. You say “I’m completely aware yk11 is bordering on more of steroid” , he says, “YK really isn’t a sarm. This demonstrates the potential of YK11 in muscle development. YK11, on the other hand, offers the potential Newbie. On the one hand, it’s an anabolic-androgenic steroid (AAS). Myogenic differentiation is in reference to the products ability to block myostatin. They're both dangerous. ) It is a partial androgen receptor agonist. Due to its steroidal backbone and the arguably labile orthoester-derived moiety positioned at the D-ring, substantial metabolic conversion in vivo was anticipated. ( 12 Reviews) Third-party tested for identity, purity, and concentration. This actually points to it being more like an anabolic steroid, because they are less targeted than SARMs. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody. The Studies Oct 16, 2023 · The need for PCT after a cycle of YK11 is a topic of debate. When using the YK11 Sarm, gaining muscle mass becomes much easier, and you’ll gain it faster. S23 and YK11 are the strongest SARMs on the market so far. Myostatin inhibits muscle growth. Take low doses of steroids, and you'll get lil to no side effects. Aug 20, 2013 · 🛑READ🛑 YK11 is a SARM and myostatin inhibitor in one! "Astounding" YK11 is a SARM and myostatin inhibitor in one Japanese researchers are doing tests with a new SARM , which according to the first publications has a stronger anabolic effect than a classic anabolic steroid such as DHT. YK11 activated the reporter gene by inducing the translocation of the AR into the nuclear compartment, where its amino-terminal domain (NTD) functions as a constitutive Dec 21, 2023 · YK11 works in different ways than the typical SARM and the side effects differ. It’s steroidal”. Stacking YK11 at 5 – 10 mg/day with RAD 140 at 15 – 20 mg/day will lead to ridiculous muscle gains. The recommended dosage of YK11 is 10-30 mg per day. It boosts your strength way beyond normal levels, increases stamina substantially, and speeds up your recovery. S. Free shipping US $100+ | international $275+. Aug 26, 2022 · YK11 actually has alot of health benefits: Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis - PubMed Muscle wasting caused by catabolic reactions in skeletal muscle is commonly observed in patients with sepsis. The best thing you can do to get good results and to avoid side effects when cycling YK11 is to make sure that you buy high-quality and to stick to normal dosages as well as a normal cycle length. It's a DHT derivative and was classified as a "SARM" because the researchers wanted more studies funded. When it is present in the body, you will experience fewer muscle gains than you would otherwise. #4. YK11 works by inhibiting myostatin, a protein that stops muscle cell growth. Jul 10, 2014 · Midwest. I think 40lbs may be a little exaggerated but I guess it would depend on the amount cycled, length, and work ethic. Nov 24, 2023 · Split the YK11 into a daily dose due to YK11’s short half life. The main difference between YK-11 and anabolic steroid is that YK-11 is more selective in its action, targeting only muscle and bone tissue, while anabolic steroids affect various tissues in the body. Compare that to Turinabol which was developed in a state sponsored program in the 60's, that lasted about 20 years. YK-11 has fewer side effects than anabolic steroids, making it a safer alternative for bodybuilding and athletic performance enhancement. I’m 33 years old and 6’1” 200 pounds with 12% body fat. Yk11 is basically a nor and very similar to the structure of testosterone so I'd consider it a steroid not a sarm. Nov 6, 2015 · Im not super stoked about it being used standalone, although it could be, but man imagine it in a potent steroid stack. Mar 19, 2022. In this post, we will review YK-11 and inform you about the benefits, side-effects, dosage and cycle recommendations of this unusual SARM. It is a synthetic steroid that tries to copy the properties of DHT, a potent substance that can be found in our bodies. LGD-4033. It's a testosterone (Test)/ 5-α-dihydrotestosterone (DHT) derivative a synthetic anabolic steroid above it are the chemical structures of Tests and DHT ( above is the chemical structure of YK-11). It's similar to a synthetic form of testosterone but with distinct advantages. Ostarine is good as well. The fact that it is also a steroid tells us that we should tread with caution when it comes to dosages, as too much of it can and will cause side effects to occur. YK11 is both a myostatin inhibitor and a SARM making it one of the most potent SARMS you can use. Also, people get scared off when you mention anabolic steroids. Soloed Rad, also soloed YK, and soloed s23. Maybe he thinks it makes him look smart. Its side effects are minimal and cannot be compared to the side effects of steroids available in the market. You should follow an 8-week or 12-week cycle for the best results with your YK11 Cardarine stack. YK11 is a steroidal selective androgen receptor modulator (SARM) and Myostatin inhibitor that was popularized because of its potential to induct supraphysiological levels of Follistatin expression. liam46 said: I had a question about using yk-11 with steroids. Oct 20, 2022 · The YK11 molecule shares many similarities with steroids, but it can be considered a non steroid SARM. YK11, also known as Myostine, is considered one of the strongest SARMs on the market. YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). YK11 binds to androgen receptors in a tissue selective manner, which is kind of the base definition of a SARM! Yet, it works somewhat differently from SARMs because it has the ability to increase follistatin. I mean, that’s a major facepalm. Aug 6, 2023 · wildman said: My experience with yk 11 is both good and bad. [1] [2] It is a gene -selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. It is considered one of the strongest SARMs on the market, alongside S-23. Sep 12, 2023 · Because of its molecular structure, many still wonder if YK-11 is actually a SARM or Steroid. The good it's game changer insane strength breaking pr's and insane physique change. $ 79. A major structural difference between YK11 and DHT is at the 17-position, where YK11 has a bulky substituent compared to DHT. Sarms are virtually just weak forms of steroids. Japanese research has proven that this SARM can lower myostatin levels in the body. tldr; YK11 is a 19-nor steroid, not a DHT derivative, with questionable oral bioavailability that is metabolized into a bunch of novel 19-nor progesterone derivatives of unknown activity. So by inhibiting the inhibitor, YK11 should elicit more pronounced muscle growth and has also been shown to be more anabolic than dihydrotestosterone (DHT). Even the stack (rad, yk, and mk) I did didn’t compare imo to the s23 by itself. Due to its steroid-like effects, YK-11 is not known to be used by women very YK11, a steroidal SARM (Selective Androgen Receptor Modulator), is gaining significant attention in the fitness community. 1. Jbswole40 Valued Member. We have previously reported that YK11 is a novel selective androgen receptor modulator (SARM) and induces myogenic differentiation and selective gene regulation. Steroid backbone YK-11 There is no reliable data available on it's liver toxicity other than it's chemical structure. This SARM never passed the preclinical development stage and has never been tested on animals or humans. Fucked lipids, raised liver enzymes, raised blood pressure, potential acne, hair loss, testosterone/estrogen suppression etc. “You take the blue pill — the story ends, you wake up in your bed and believe whatever you want to believe. Jul 9, 2020 · Classified as a selective androgen receptor modulator, YK11 is known for its unique ability to grow muscles and promote growth. Oct 15, 2022 · The results of the docking study of AR-LBP and YK11 showed that the steroid core structure of YK11 was in a position surrounded by a similar set of residues for DHT binding (Fig. YK11 was first studied by Japanese researcher Yuichiro Kanno in 2011. #2. IronMag Labs Hardcore Bodybuilding Supplements. Jan 1, 2024 · RAD 140 as the primary muscle builder, paired with YK11 as a secondary muscle builder and myostatin inhibitor, and lastly MK677 as a GH and IGF-1 secretagogue. 17 alpha alkylation (17aa) is the addition of an alkyl group to the alpha position of the 17th carbon of the steroid backbone. Felt bigger, looked bigger. A. For instance, a Biological & Pharmaceutical Bulletin study found that YK11 induced muscle cell growth more effectively than DHT, a potent anabolic steroid. , and they are still being studied. I know both these sarms are very new to the sarms world, but I am a risk taker and would like to stack them both together, S23 and YK11. Apr 5, 2024 · This means that S23 and other SARMs will work very similarly to steroids and won’t have that many side effects. That tells all we need to know about just how incredibly powerful YK-11 is! YK-11 Cycle for Women. The first is that is a myostatin inhibitor. Induction sealed and batch coded. It is as selective as Anavar or winny basically. More specifically, it’s a Myostatin inhibitor. It is best not to use YK11 or RAD 140 since they are unlawful and can result in severe negative consequences. 60 Capsules per pouch YK11, also known as Myostine, is considered one of the strongest SARMs on the market. They target androgen receptors in your body to increase muscle mass and bone density. Decent strength gains on rad but YK gave me a fuller feeling. In the AR-positive human breast cancer MDA-MB-453 cells, different patterns of AR-mediated target gene expression and AR recruitment to their enhancer regions were observed between DHT and YK11. Myostatin inhibitors work by allowing the body to develop or increase muscular capacity at a rate faster than the body can do on its own. Let’s not forget – a balanced cycle is key in ensuring your body gets the most mileage from The phosphorylated Akt protein level was increased by YK11 and DHT treatment, suggesting that YK11 activates Akt-signaling via non-genomic signaling of AR. We find users typically gain up to 15 pounds of lean muscle from a RAD 140 cycle and lose approximately 3% of body fat. Dec 5, 2018 · YK-11 just like any other SARM is designed to help with muscle growth. Reply Oct 15, 2022 · In this study, we investigated the selective mechanism using the synthetic steroid YK11, which showed AR-mediated gene-selective transactivation. In fact, it’s so strong and has a comparable anabolic activity to steroids that it may actually be a synthetic steroid that was mislabeled a SARM in the first place. It mainly works as a myostatin inhibitor. I have used most of the other sarms arleady with good results. Estrogen is the only issue you would have to worry shit with steroids unless you're abusing them, and enlarging your heart, and prostate. Week 1-12 – 20mg/day GW-501516 (Cardarine) 30 minutes before workout. xy us ya ye as np ra ya jt hb