Phenylephrine vs pseudoephedrine. Senate passed a bill restricting its sale.

Jan 21, 2006. S. Apr 1, 2024 · The decongestants in these combinations, phenylephrine, and pseudoephedrine produce a narrowing of blood vessels. Prescribed for Weight Loss (Obesity/Overweight), Cold Symptoms, Nasal Congestion. 36% of reviewers reported a positive effect, while 55% reported a Phenylephrine is a medication used as a decongestant for uncomplicated nasal congestion, [3] used to dilate the pupil, used to increase blood pressure (given intravenously in cases of low blood pressure ), and used to relieve hemorrhoids. So if you react phenylephrine with phosphorous and iodine it only the OH in the green circle is affected. 86% of reviewers reported a positive effect, while 0% reported a negative effect. Senate passed a bill restricting its sale. Mar 25, 2022 · Horak F, Zieglmayer P, Zieglmayer R, et al. 5. 5,20 Terbutaline, a beta 2-agonist with minor beta 1 effects, is thought to have some alpha-agonist activity promoting smooth-muscle relaxation. Mar 30, 2022 · Pseudoephedrine is an adrenergic receptor ligand, but it has far less stimulating properties than methamphetamine and a better pharmacological profile than ephedrine. Phenylephrine (Sudafed PE) isn't a first-choice option for people who are pregnant or breastfeeding because there's a chance that it can affect the growing Feb 9, 2024 · Among the phenylephrine-containing formulations, 85. Other beneficial effects may include increasing the drainage of sinus secretions, and opening of Sep 22, 2023 · Pseudoephedrine is also a nasal decongestant and works the same way that phenylephrine does: by relieving sinus congestion and pressure due to colds or allergies. For those with high blood pressure, phenylephrine is an alternative to pseudoephedrine. 24-hour extended-release: 240 mg orally every 24 hours as needed. You may opt to use Mucinex if your symptoms are I took pseudoephedrine (2 - 30mg pills) and 10 mg phenylephrine together. Ratings & Reviews. Illustration by Annemarie Johnson, Vivo Visuals Studio. A third, phenylpropanolamine Dec 18, 2023 · Phenylephrine nasal spray (Neo-Synephrine) isn’t affected by the FDA’s ruling and is still considered effective. I t’s easy to understand how a medicine like phenylephrine got onto pharmacy shelves in the first place. phenylephrine nasal may also be used for purposes not listed in this medication guide. The common decongestant, used most often as an ingredient Nov 6, 2023 · Guaifenesin and phenylephrine may cause serious side effects. Sep 13, 2023 · That would likely force consumers to switch to the behind-the-counter pseudoephedrine products or to phenylephrine-based nasal sprays and drops. feeling restless or excited (especially in children). Sep 14, 2023 · The DEA places strict limits on the dose and number of pseudoephedrine-containing products patients may obtain within a 30-day time frame. Pseudoephedrine (Sudafed) is a decongestant that interacts with some antidepressants, alcohol, and caffeine. Flonase and Phenylephrine are two such drugs commonly used to manage these conditions. Mar 5, 2024 · Common side effects of dextromethorphan, guaifenesin, and phenylephrine may include: diarrhea, constipation; dizziness, drowsiness; sleep problems (insomnia); or. Both pseudoephedrine and phenylephrine are decongestants used to treat nasal congestion due to allergies, colds, sinus infections, etc. Decongestants are often in over-the-counter medications used to treat nasal congestion (“stuffy nose”) caused by colds or allergies. There is some controversy over whether it works at the dosages usually found in over-the-counter more. Ann Allergy Asthma Immunol. Obat ini bekerja dengan cara mengurangi pembengkakan Immediate release: 30 mg orally every 4 to 6 hours as needed. They can help ease the symptoms of conditions such as colds and flu, hay fever and other allergic reactions, catarrh and sinusitis. wanderer@vumc. Sep 22, 2023 · The drug, known as phenylephrine, was previously a go-to drug for sinus pressure and congestion, after another nasal decongestant known as pseudoephedrine had its availability restricted. The Nov 6, 2023 · This means that while phenylephrine-containing Sudafed PE is available on store shelves, you probably have to ask a pharmacist and show ID to purchase regular Sudafed, which contains pseudoephedrine. It reduces tissue hyperemia, edema, and nasal congestion commonly associated with colds or allergies. Jul 20, 2006 · Pseudoephedrine: Evaluative trials regarding oral decongestant use in hypertensive patients are quite limited. Phenylephrine is available as a standalone medication, or as part of a multidrug More about Sudafed Children's Nasal Decongestant ( pseudoephedrine ) Ratings & Reviews. In that scenario, the FDA would have to work with Dec 2, 2020 · Bottom Line – Phenylephrine vs Pseudoephedrine Both drugs are decongestants used to treat nasal congestion because of colds, allergies, or sinus infections. Ephedrine acts as both a direct and indirect sympathomimetic. Dr Fowler and 2 doctors agreed. This fast-acting decongestant formula helps to temporarily relieve sinus pressure and congestion caused by the common cold, hay fever or other allergies. Find out why pseudoephedrine is more potent and preferred over phenylephrine for nasal congestion. No adverse events were reported in this study. These structural differences give pseudoephedrine its unique stereochemistry. 1 out of 10 from a total of 22 ratings on Drugs. Meski obat batuk dan flu biasanya dijual bebas tanpa resep, salah satu dari kedua zat ini jika disalahgunakan sebagai psikotropika, bisa sangat berbahaya dan menyebabkan kecanduan. Die Medikamente sind auch in verschiedenen Kombinationen mit anderen rezeptfreien Husten- und Erkältungsmedikamenten erhältlich. 12 The American College of Obstetricians and Gynecologists (ACOG) and the American College of Allergy, Asthma and Immunology (ACAAI) recommend using pseudoephedrine during pregnancy. The amount of pseudoephedrine that an individual can purchase each month is limited and individuals are required to present photo identification to purchase products containing pseudoephedrine. There has been increasing concern that these active substances can be extracted from over-the-counter (OTC) medicines and Aug 19, 2019 · Pseudoephedrine is often first-line due to its -agonist effects analogous to the vasoconstrictive properties of phenylephrine. Find out how pseudoephedrine treats a blocked or stuffy nose, and how to take it. Rathmell, Brigham and Women’s Health Care/Harvard Medical School. Pseudoephedrine is typically taken as a tablet or capsule, and is also usually intended or short-term relief of nasal congestion. Prescribed for Nasal Congestion. Phenylephrine's more effective cousin: pseudoephedrine . Note that either pseudoephedrine or phenylephrine can be found in cough/cold formulations, allergy and asthma medications, hemorrhoid creams, and Mar 19, 2024 · The Current Status of Oral Phenylephrine as a Nasal Decongestant with Dr. Jul 11, 2023 · Phenylephrine (Sudafed PE) is a decongestant used to treat nasal and sinus congestion from allergies and the common cold. Follow the instructions on the medicine label. Aug 21, 2023 · Less serious pseudoephedrine side effects may include: loss of appetite; warmth, tingling, or redness under your skin; feeling restless or excited (especially in children); sleep problems (insomnia); or. Phenylephrine has an average rating of 6. Due to its central nervous system (CNS) stimulant properties and structural similarity to amphetamine, it is also used for non-medical purposes. Sudafed is also used to relieve nasal congestion due to the common cold. Sep 13, 2023 · Phenylephrine became the main ingredient in over-the-counter decongestants in the U. Dec 11, 2014 · Pseudoephedrine and ephedrine are medicines used as nasal decongestants. They each work differently but both have a decongesting effect on patients suffering from allergic rhinitis or common colds. 21 Terbutaline was compared with pseudoephedrine and placebo in one study Mar 30, 2024 · Phenylephrine vs Pseudoephedrine - How do they compare? Updated 24 Oct 2023 1 answer FAQ by Drugs. Pseudoephedrine has the chemical formula C10H15NO. D. But the hydroxyl group in the blue circle (called a phenolic group) is chemically unreactive. Pseudoephedrine, the decongestant found in Sudafed, is highly effective in helping people with stuffy noses breathe more easily, said Dr. The unanimous vote of the Nonprescription May 8, 2024 · Chemical Structure of Pseudoephedrine. i am a 26 year old male, 280 lbs. Pseudoephedrine vs. should i be concerned? A doctor has provided 1 answer A member asked: Phenylephrine relieves congestion of the nasal passages and is found in many cold and flu remedies. Do not to exceed 2 doses/24 hr for 3 to 5 days. Check with your doctor as soon as possible if any of the following side effects occur while taking pseudoephedrine: Rare Sep 12, 2017 · The second reaction (below) is quite different. Oleh karena itu, BPOM melakukan pengawasan penuh terhadap Mar 21, 2023 · Phenylephrine is also available as nasal drops. skin rash or itching. A. From the #1 pharmacist recommended Oct 31, 2018 · The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. [2] [4] It can be taken by mouth, as a nasal spray, given by injection into a vein or muscle, or applied to Enter another drug to compare. Jan 12, 2024 · Ingredients in Nasal Decongestants. Consequently, the medication is an optimal choice for raising mean arterial pressure by inducing vasoconstriction in both veins and arteries and enhancing cardiac preload without exerting significant effects on cardiac myocytes. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure. Pseudoephedrine is also at times abused, and its use is regulated Mar 17, 2024 · The recommended dose of oxymetazoline is 2 or 3 sprays in each nostril. Phenylephrine relieves congestion of the nasal passages and is found in many cold and flu remedies. Let your provider know if your pregnant or breastfeeding because you might need to use a different medication. Although not all of these side effects may occur, if they do occur they may need medical attention. Benadryl is also an antihistamine used to treat other allergy symptoms (including hives, itching, watery eyes), insomnia, motion sickness, and mild cases of Parkinsonism. Claritin-D, Mucinex-D, Benadryl-D, Sudafed, and Sudafed-PE). Side effects include temporary burning or stinging in the eye, blurry vision, and possibly raise your blood pressure. Prescription and OTC. It helps to relieve stuffiness and sinus congestion or pressure due to the common cold or seasonal allergies. Talk with the doctor before giving Sep 14, 2023 · September 14, 2023 4:30 PM EDT. Ryan Phasouk answered. after pseudoephedrine, another drug, was restricted because it can be used to make methamphetamine. Following overdose in children, these agents have the potential to cause serious toxicity including agitation, hypertension, and cardiac arrhythmias. Pseudoephedrine (Sudafed), oxymetazoline (Afrin), and fluticasone propionate (Flonase) are top examples. Oregon and Mississippi lawmakers went even further. , pseudoephedrine, ice), urgent return to clinic with anticipated phenylephrine injection, or referral to the emergency department. However, a 2009 study done at the ENT University Clinic, University of Vienna, Austria, concluded that pseudoephedrine is considerably more effective than phenylephrine in the treatment Obat-obatan atau suplemen, seperti pil diet, pil kafein, obat ADHD, serta monoamine oxidase inhibitors (MAOI), termasuk isokarboksazid, fenelzin (Nardil), selegiline, dan tranylcypromine, juga sebaiknya tidak dikonsumsi bersamaan dengan pseudoephedrine atau phenylephrine. They achieve this through their action as alpha-adrenergic agonists, stimulating receptors that cause vasoconstriction or narrowing of blood vessels. Each tablet contains 10 mg phenylephrine HCL, a powerful nasal decongestant that reduces swelling and provides sinus pressure relief for easier breathing. These medications are often used to treat nasal and chest congestion. Benadryl and Sudafed belong to Jul 15, 2020 · Phenylephrine is a type of nasal decongestant in over-the-counter (OTC) medications, such as Sudafed PE. Although there haven’t been studies measuring Ephedrine has an average rating of 9. TIL that Phenylephrine, the nasal decongestant that replaced pseudoephedrine in OTC cold medicine, was shown to be ineffective vs placebo at up to 4X the recommended dose, and was not well tolerated starting at 4X the recommended dose. Conclusions: During a 6-hour observation period, a single dose of pseudoephedrine but not phenylephrine resulted in significant improvement in measures of nasal congestion. 60% of reviewers Sep 13, 2023 · Sept. Recently Salerno et al. Call your doctor for medical advice about side effects. Phenylephrine? Updated 21 Sep 2017 4 answers. Complex Information for Anesthesiologists Presented Quickly and ClearlyInfographic created by Jonathan P. It also comes in longer-acting versions that are taken every 12 or 24 hours, depending on the dose. phenylpropanolamine may also be used Lower-cost generic is available. Apr 12, 2023 · Used for Nasal Congestion. Diese Medikamente sind beide nasalabschwellende Mittel. Some people still notice amphetamine-like effects of sleeplessness and jitters at those Decongestants are a type of medicine that can provide short-term relief for a blocked or stuffy nose (nasal congestion). 63% of reviewers reported a positive effect, while 37% reported a negative effect. Unlike pseudoephedrine, which can raise blood pressure and make people feel a little Neither phenylephrine nor pseudoephedrine had an effect on the nonnasal symptoms. Phenylephrine has also been used to treat temporary low blood pressure caused by anesthesia used during Phenylephrine eye drops are used to dilate (widen) pupils for eye exams or certain eye procedures. 8% of pseudoephedrine-containing Apr 18, 2024 · Pseudoephedrine and loratadine (Claritin-D) Decongestant nasal sprays. , NyQuil Severe Cold & Flu and Tylenol . feeling nervous, restless, or irritable. As a cold medicine, this The decongestants, such as phenylephrine, and pseudoephedrine, produce a narrowing of blood vessels. NHS medicines information on pseudoephedrine – what it's used for, side effects, dosage and who can take it. Pseudoephedrine can be made into illegal methamphetamine, a highly addictive drug Aug 24, 2023 · Sudafed works as a decongestant. E. Sie werden zur kurzfristigen Linderung von Verstopfung und Druck in den Dec 1, 2023 · That made the medication harder to access, so some people turned to another oral decongestant, phenylephrine. This is not a complete list of side effects and others may occur. Examples include: Oxymetazoline (Afrin, Zicam) Phenylephrine hydrochloride (Neo Pseudoephedrine dan Phenylephrine merupakan dua jenis kandungan yang terdapat dalam obat batuk dan flu. It can cause side effects such as headaches, nervousness, and difficulty sleeping. 3 out of 10 from a total of 21 ratings on Drugs. 2009;102(2):116-120. Jun 30, 2014 · Dr. Phenylephrine is a decongestant. Benadryl (diphenhydramine) and Sudafed (pseudoephedrine HCI) are used to treat nasal congestion due to allergies. increased blood pressure--severe headache, blurred vision, pounding in your neck or ears. Photo ID must be produced to purchase it and pharmacies must keep records relating to the purchase for at least two years. two of the "old" sudafed tabs (total = 60 mg pseudoephedrine). Along with its needed effects, pseudoephedrine may cause some unwanted effects. Neither phenylephrine nor pseudoephedrine Jul 18, 2016 · For instance, Sudafed Congestion contains pseudoephedrine, but Sudafed PE Congestion contains phenylephrine. Since pseudoephedrine can be made into methamphetamine, the U. 7 out of 10 from a total of 222 ratings on Drugs. It can be hard to choose the right medication when you are Oct 25, 2023 · Serious side effects of Pseudoephedrine. Other typical May 3, 2022 · Maxi-Tuss PE Jr: Each 5 mL contains 50 mg of guaifenesin and 2. Stop using guaifenesin and phenylephrine and call your doctor at once if you have: nervousness, dizziness, sleep problems ( insomnia ). Pseudo: Pseudoephedrine has been consistently proven in clinical studies to be superior when compared with phenylephrine. Phenylephrine can be found in different products, including Sudafed PE. Maximum dose: 240 mg in 24 hours. There are several alternatives to phenylephrine you can consider. Pseudoephedrine products can still be purchased in limited quantities, but identification and Sudafed enthält Pseudoephedrin, während Sudafed PE Phenylephrin enthält. Ilisa Bernstein So, although pseudoephedrine is effective, those hurdles make it difficult and Mar 15, 2006 · Pseudoephedrine and phenylephrine are pregnancy category C in all three trimesters of pregnancy. Phenylephrine merupakan obat golongan dekongestan. 4 performed a meta-analysis (MA) of some pertinent available pseudoephedrine studies in an attempt to provide more conclusive information regarding the safety of these products in hypertensive patients. 5 out of 10 from a total of 89 ratings on Drugs. Feb 25, 2020 · Learn how phenylephrine and pseudoephedrine work as nasal decongestants, their effectiveness, side effects, and cost. Oct 20, 2005 · 2. This can help reduce chest congestion and make coughs more productive. Oct 28, 2023 · Phenylephrine has been the only oral decongestant on pharmacy and grocery store shelves since another popular decongestant, pseudoephedrine, became more regulated and went behind the counter in 2006. Konsultasikan dengan dokter jika Anda sedang menjalani pengobatan medis May 13, 2021 · Pseudoephedrine (PSE) is a drug with a long history of medical use; it is helpful in treating symptoms of the common cold and flu, sinusitis, asthma, and bronchitis. Find out their uses, side effects, interactions, and potential for misuse. Oxymetazoline nasal has an average rating of 4. 60% of reviewers reported a positive effect, while 30% reported a negative effect. Material and methods: Patch tests with 10% phenylephrine and 10% pseudoephedrine in petrolatum, and 10% and 20% ephedrine, 10% phenylpropanolamine, 5% fepradinol, 1% methoxamine, and 10% oxymetazoline, all administered in dimethyl sulfoxide (DMSO), were carried out in 14 patients with a history of allergy to any of these drugs. 5 mg of phenylephrine. 13, 2023 -- America's most popular oral nasal decongestant, phenylephrine, is not effective and no better than a placebo, an FDA panel said Tuesday. Both ingredients are safe for short-term use. Some of these combinations are available only with your doctor's prescription. The US Food and Drug Administration (FDA Pseudoephedrine (Sudafed) Other brand names: Galpseud, Boots Decongestant, Care Decongestant. Different forms of Suphedrine (pseudoephedrine capsules and tablets) may be for use in different ages of children. Sleeplessness is a common side effect. severe dizziness or nervousness; sleep problems ( insomnia ); or. Aug 30, 2023 · Pseudoephedrine effectively relieves nasal congestion and is found in several behind the counter combination cold and flu remedies. Aug 4, 2023 · Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu. Maximum dose: 120 mg in 24 hours. Mucinex is an expectorant. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Pseudoephedrine. Justine has been a Registered Nurse for 10 years and has a Bachelor's of Science in Nursing degree. It's available over the counter as tablets and a liquid solution. 12 years or older: Immediate release: 30 to 60 mg orally every 4 to 6 hours as needed. Wanderer: jon. 0 out of 10 from Phenylephrine. Some people prefer nasal sprays because they work in the nose while other people prefer to take tablets or capsules. It is commonly used every 4 hours. Common side effects of phenylephrine may include: flushing (warmth, redness, or tingly feeling); loss of appetite; or. They work by reducing the swelling of the blood vessels in your nose, which helps to open the Pseudoephedrine and phenylephrine are popular ingredients in OTC decongestant products (e. org. It loosens mucus and thins secretions in the lungs. 0 out of 10 from a total of 9 ratings on Drugs. 5% contained three or more active ingredients, most commonly analgesics and antitussives, compared with 15. Adults and children 12 years of age or older: The typical dose is 4 teaspoonfuls (20 mL) by mouth every 4 hours. It's available in a short-acting version that's taken once every 4 to 6 hours. You can buy products containing phenylephrine right off the shelf at the pharmacy. Your healthcare team can help you avoid serious interactions with pseudoephedrine. Pseudoephedrine effectively relieves nasal congestion and is found in several behind the counter It is the Panel’s opinion that these must be managed using the clinician’s best judgment and may lead to recommendations of observation with status updates, oral or topical therapies (e. Sudafed (pseudoephedrine) is a non-drowsy decongestant taken by mouth to treat nasal and sinus congestion from allergies and the common cold. Jan 27, 2024 · Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Phenylephrine contains two different hydroxyl (OH) groups, as shown in the blue and green circles. Antihistamines, such as loratadine (Claritin), can be Sep 12, 2023 · The F. Address correspondence to Dr. Other decongestants are available to buy from pharmacies or shops, such as xylometazoline nasal sprays and phenylephrine capsules. Comparing Phenylephrine vs Pseudoephedrine. Phenylephrine adalah obat untuk meredakan hidung tersumbat karena flu, batuk pilek, alergi, atau sinusitis. Pseudoephedrine is a decongestant, which means it helps dry up a runny nose. The two most common ingredients in OTC nasal decongestants are pseudoephedrine and phenylephrine. DMSO was used as Oct 30, 2023 · Phenylephrine primarily acts as an alpha-1 adrenergic receptor agonist and exhibits minimal to no beta-adrenergic activity. Oh, and one thing that I just noticed (I found a box of normal sudafed in the medicine cabinet) - the PE tabs look almost identical to the old pseudoephredine tabs, BUT the adult dosage is one of the PE tabs (10mg Phenylephrine) vs. May 8, 2023 · Ephedrine, a stereoisomer to better-known pseudoephedrine, is a sympathomimetic amine with unique effects due to its indirect mechanism than other sympathomimetic agents like pseudoephedrine and phenylephrine. Pseudoephedrine is also a nasal decongestant and works the same way that phenylephrine does: by relieving sinus congestion and pressure due to colds or allergies. Jun 11, 2019 · Here are some of the most common active ingredients in cold and flu medications and what they do. Pseudoephedrine has an average rating of 6. Answered 6/30/2014. There's another oral decongestant that works similarly, pseudoephedrine, and research has shown for a while that it's more effective than Pseudoephedrine is a stimulant, but it is well known for shrinking swollen nasal mucous membranes, so it is often used as a decongestant. Sudafed Children's Nasal Decongestant has an average rating of 1. It is famous for drying nasal passages during colds and allergies, at which it excels. Sep 12, 2023 · That would likely force consumers to switch to the behind-the-counter pseudoephedrine products or to phenylephrine-based nasal sprays and drops. It can also interact with phentermine (Adipex-P, Lomaira), digoxin, and blood pressure medications. This topic will discuss the clinical features, diagnosis, and management of poisoning caused by phenylephrine and related decongestants. Jun 21, 2024 · The bottom line. com. These work faster than tablets or capsules. Bottom Line. Aug 31, 2023 · 4. They are in the same drug class known as nasal decongestants, which help relieve sinus congestion and pressure. Specializes in Family Medicine. Over-the-counter. Obat ini efektif untuk meredakan gejala, tetapi tidak bisa menyembuhkan penyakit yang menjadi penyebab hidung tersumbat. Phenylephrine is more widely available, but does not work well at its job. WATCH: The promises and potential pitfalls of Oct 25, 2023 · When the Combat Methamphetamine Epidemic took effect in 2006, there were only two over-the-counter oral decongestants on the market: phenylephrine and pseudoephedrine. Don't take more than 24 teaspoonfuls (120 mL) in a 24-hour period or as directed by your provider. Pseudoephedrine and phenylephrine are both used to manage the symptoms of nasal congestion by shrinking swollen blood vessels in the nasal passages. Use with Suphedrine (pseudoephedrine capsules and tablets) may cause nervousness, shakiness, and a fast heartbeat. Flonase is a corticosteroid spray which affects inflammatory responses, reducing swelling and irritation in the nose. Theresa Michele and Dr. There is some controversy over whether it works at the dosages usually found in over-the-counter products. Pseudoephedrine is the active ingredient in original Sudafed, and it constricts blood vessels. #2. Phenylephrine. will make its own decision on whether to remove medications containing the ingredient, phenylephrine, which is found in products like Sudafed P. g. 12-hour extended- release: 120 mg orally every 12 hours as needed. Jan 29, 2020 · Phenylephrine. Phenylephrine comes as a liquid, a tablet, or a dissolving strip to take by mouth. Pseudoephedrine effectively relieves nasal congestion and is found in several behind the counter combination cold and flu remedies. Maryann Amirshahi, a medical toxicologist Feb 17, 2023 · Learn the differences and similarities between pseudoephedrine and phenylephrine, two common ingredients in nasal decongestants. Eucalyptus, menthol and camphor are used in Vaporub. However, intravenous or oral administration of phenylephrine might decrease milk production. Similar to phenylephrine, it features a phenyl group and an amino group but differs due to an additional methyl group on the nitrogen and a second chiral carbon atom. A placebo-controlled study of the nasal decongestant effect of phenylephrine and pseudoephedrine in the Vienna challenge chamber. Wanderer, Vanderbilt University Medical Center, and James P. However, this drug has a much stronger effect than phenylephrine. ha kk je vf sv vo yu cy gf cm